Epstein M R, Saul J P, Fishberger S B, Triedman J K, Walsh E P
Children's Hospital, Department of Cardiology, Boston, MA 02115, USA.
Pacing Clin Electrophysiol. 1997 Jun;20(6):1654-61. doi: 10.1111/j.1540-8159.1997.tb03535.x.
Between May 1990 and March 1995, 5 of 29 young patients (ages 4.2-25 years; median 14.1 years) undergoing RF ablation for atrioventricular node reentrant tachycardia (AVNRT) presented with spontaneous accelerated junctional rhythm (AJR) (CL = 500-750 ms), compared to 0 of 58 age matched controls undergoing RF ablation for a concealed AV accessory pathway (P = 0.004). In 3 of the 5 patients with AVNRT and AJR, junctional beats served as a trigger for reentry. During attempted slow pathway modification in the five patients with AVNRT and AJR, AVNRT continued to be inducible until the AJR was entirely eliminated or dramatically slowed. These 5 patients are tachycardia-free in followup (median 15 months; range 6-31 months) with only 1 of the 5 patients continuing to experience episodic AJR at rates slower than observed preablation. Episodic spontaneous AJR is statistically associated with AVNRT in young patients and can serve as a trigger for reentry. Successful modification of slow pathway conduction may be predicted by the elimination of AJR or its modulation to slower rates, suggesting that the rhythm is secondary to enhanced automaticity arising near or within the slow pathway.
1990年5月至1995年3月期间,29例接受房室结折返性心动过速(AVNRT)射频消融术的年轻患者(年龄4.2 - 25岁;中位数14.1岁)中有5例出现自发加速性交界性心律(AJR)(周期长度=500 - 750毫秒),而58例接受隐匿性房室旁路射频消融术的年龄匹配对照患者中无1例出现(P = 0.004)。在5例AVNRT合并AJR的患者中,有3例交界性搏动作为折返的触发因素。在对这5例AVNRT合并AJR的患者进行慢径路改良尝试过程中,直到AJR完全消除或显著减慢之前,AVNRT一直可被诱发。这5例患者在随访中(中位数15个月;范围6 - 31个月)无心动过速发作,5例患者中只有1例继续出现比消融前观察到的速率更慢的间歇性AJR。年轻患者中,间歇性自发AJR与AVNRT在统计学上相关,且可作为折返的触发因素。消除AJR或将其调制为更慢的速率可能预示着慢径路传导改良成功,提示该心律继发于慢径路附近或内部增强的自律性。