Miyahara S, Nakada M, Nishizaki K, Kawarai Y, Nishioka K, Hino H
Department of Otolaryngology, Okayama University Medical School, Japan.
Acta Med Okayama. 1997 Jun;51(3):167-71. doi: 10.18926/AMO/30796.
We studied 92 patients with allergic rhinitis in Syodoshima, Japan, during the pollen season between April and June to evaluate the cross-reactivity to different antigens, including pollen from the olive tree (Olea europaea) and orchard grass (Dactylis glomerata). Olive tree pollen was present in the atmosphere for 23 days, from May 19 to June 12, 1994. Specific IgE antibodies for olive tree pollen antigen were present in 21 (26.9%) of the 78 patients with allergic rhinitis. Nine (24.3%) of the 37 patients with allergic rhinitis exhibited positive skin reactivity to an extract of olive tree pollen. Fifteen (88.2%) of the 17 patients who had IgE reactivity in their sera to olive tree pollen antigen demonstrated allergic reactions to an extract of olive tree pollen. Specific IgE antibodies for orchard grass pollen antigen were present in 43 (48.3%) of the 89 patients with allergic rhinitis and 20 (95.2%) of the 21 patients who had IgE reactivity in their sera to olive tree pollen antigen. The inhibition test using the CAP System revealed that the reactivity of the IgE antibody specific for olive tree pollen antigen was inhibited dose-dependently by an extract of orchard grass pollen. These findings show that there is a reaction in some patients with grass (Gramineae) pollinosis that might be induced by olive tree pollen.
我们在日本小豆岛对92例变应性鼻炎患者进行了研究，研究时间为4月至6月的花粉季节，以评估对不同抗原的交叉反应性，这些抗原包括油橄榄花粉（油橄榄）和果园草花粉（鸭茅）。1994年5月19日至6月12日，大气中存在油橄榄花粉23天。78例变应性鼻炎患者中有21例（26.9%）存在针对油橄榄花粉抗原的特异性IgE抗体。37例变应性鼻炎患者中有9例（24.3%）对油橄榄花粉提取物表现出阳性皮肤反应。血清中对油橄榄花粉抗原有IgE反应性的17例患者中有15例（88.2%）对油橄榄花粉提取物出现过敏反应。89例变应性鼻炎患者中有43例（48.3%）以及血清中对油橄榄花粉抗原有IgE反应性的21例患者中有20例（95.2%）存在针对果园草花粉抗原的特异性IgE抗体。使用CAP系统进行的抑制试验显示，针对油橄榄花粉抗原的IgE抗体反应性被果园草花粉提取物剂量依赖性地抑制。这些发现表明，一些禾本科花粉症患者的反应可能由油橄榄花粉诱发。
