Barone J H, Fishbein M C, Czer L S, Blanche C, Trento A, Luthringer D J
Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.
J Heart Lung Transplant. 1997 Jun;16(6):600-3.
The clinical records and autopsy material from 14 patients treated with cyclosporine who were not recipients of cardiac allografts were reviewed to further study the nature of endocardial lymphoid infiltrates (quilty lesions). Although there was well-documented exposure to cyclosporine, no endocardial lymphoid infiltrates were identified in these cases, providing evidence that the endocardial-based Quilty lesion is not the result of the direct effect of cyclosporine and may represent a localized form of heart rejection confined to the endocardium.
回顾了14例接受环孢素治疗但未接受心脏同种异体移植患者的临床记录和尸检材料，以进一步研究心内膜淋巴样浸润（奎尔蒂病变）的性质。尽管有充分记录表明这些患者接触过环孢素，但在这些病例中未发现心内膜淋巴样浸润，这证明基于心内膜的奎尔蒂病变不是环孢素直接作用的结果，可能代表局限于心内膜的一种心脏排斥的局部形式。
