[Research of Academician O.V. Palladin and his school in the field of biochemistry and physiology of muscles].

The paper deals with the history of development of one of the basic trends in scientific activity of Academician O. V. Palladin and world-known biochemical school created by him: biochemistry and physiology of muscular activity. Retrospective analysis of the works by O. V. Palladin and his pupils, dedicated to the mentioned problem permits judging of realization of his ideas, when studying the process of training, work to fatigue by means of determining the content of energy sources in muscles (creatine, creatine phosphoric acid, carnosine cholesterin, glycogen), some redox enzymes (catalase, dehydrogenases), lactic acid, vitamins (ascorbic acid, B1). It is emphasized that the scientific legacy of O. V. Palladin's school is of great practical importance for rational substantiation of regimes of physical loads of sportsmen and physical culture men, production sphere workers. The works of this school have exerted considerable influence on the solution of labour physiology problem.