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[Experimental therapy of perforating wounds of cornea with adhelon].

作者信息

Gundorova R A, Khoroshilova-Maslova I P, Chentsova E V, Ilatovskaia L V, Iamskova V P, Romanova I I

机构信息

NII of Eye Diseases of Gelmogolts, Moscow.

出版信息

Vestn Oftalmol. 1997 Mar-Apr;113(2):12-6.

PMID:9229895
Abstract

The efficacy of Adhelon, a new stimulator of repair regeneration belonging to the group of adhesion factors, was experimentally assessed in the treatment of ocular injuries on a model of perforating untreated wound of the cornea. Clinical and histologic studies in two groups of rabbits persuasively demonstrated the benign effect of adhelon on the course of wound process: the period of inflammatory reaction shortened, infectious complications were prevented, the wound edges closed sooner, epithelialization and reconstruction of newly formed cicatricial tissue was accelerated. Application of adhelon led to the formation of more delicate, compact, and vessel-free cicatrices and accelerated the repair regeneration of the wounded cornea.

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