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Influence of twist on vein and PTFE graft hemodynamics: an ex vivo experimental study.

作者信息

Karacagil S, Bowald S, Almgren B, Bergqvist D

机构信息

Department of Surgery, University Hospital, Uppsala, Sweden.

出版信息

Panminerva Med. 1997 Jun;39(2):95-9.

PMID:9230617
Abstract

OBJECTIVE

In an ex vivo infusion model, the effect of different factors affecting the critical level of twist in vein and PTFE grafts was analysed.

SETTING

University Hospital, Department of Surgery.

EXPERIMENTAL DESIGN

Saline perfusion of grafts with various diameter and length under constant high (90 ml/min) and low (50 ml/min) flow rates against various peripheral resistance was performed.

MEASURES

The pressure changes in the grafts were measured at increasing increments of twisting.

RESULTS

The critical level of twist appears to be dependent on the diameter, length, stretching, status of peripheral resistance, amount of volume flow and the type of graft material, varying between 90 to more than 360 degrees. In vein grafts critical twisting appeared earlier with a decrease in diameter, shortening in length, high peripheral resistance, high flow rate and stretching. PTFE grafts especially with external spiral support were resistant to twist.

CONCLUSIONS

These data suggest that the critical level of graft twist is dependent upon multiple factors and moderate or even high grade twist with especially externally supported PTFE grafts regardless of length and long mobilized vein grafts do not lead to hemodynamic changes. On the other hand total cessation of flow occurs at lower degrees of twist in stretched, short vein grafts.

摘要

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