Pellicciari C, Rossi G, Verzura P, Marini G
Basic Appl Histochem. 1979;23(1):53-7.
A cytochemical study of a case of acute myelomonocytic leukaemia, which arose after radiation therapy and polychemotherapy for Hodgkin's disease, is presented. The distribution of the DNA content of the circulating blood cells appears to be different from the unimodal diploid distribution reported in the literature for acute myelomonocytic leukamias not associated with therapy. This finding seems to strengthen the hypothesis, already put forward by Marinone et al. (1979), that a particular pattern of DNA content distribution could be characteristic of leukaemias linked to chemotherapy and radiotherapy.
本文介绍了一例急性粒单核细胞白血病的细胞化学研究，该病例发生于霍奇金病放疗和多药化疗之后。循环血细胞的DNA含量分布似乎与文献报道的非治疗相关性急性粒单核细胞白血病的单峰二倍体分布有所不同。这一发现似乎强化了Marinone等人（1979年）已经提出的假说，即特定的DNA含量分布模式可能是与化疗和放疗相关白血病的特征。
