Dubois M, Wilson T W
Hypertension Clinic, Royal University Hospital, Saskatoon, Saskatchewan.
Can Nurse. 1997 Jun;93(6):31-4.
Hypertension is a major risk factor for cardiovascular disease. It affects approximately one in five, or 20 per cent of Canadians. The consequences of untreated hypertension include myocardial infarction, stroke, congestive heart failure, peripheral vascular disease and renal disease. By lowering a person's diastolic blood pressure 5 to 6 mmHg, their chances of having a stroke are reduced by 35 to 40 per cent and 20 to 25 per cent for coronary heart disease. While the treatment for hypertension includes both nonpharmacological and pharmacological therapy, this article will explore losartan or Cozaar, which falls under the newest class of antihypertensive drugs, angiotensin II antagonists.
高血压是心血管疾病的主要风险因素。大约每五个加拿大人中就有一人受其影响，即20%的加拿大人。未经治疗的高血压会导致心肌梗死、中风、充血性心力衰竭、外周血管疾病和肾病。将一个人的舒张压降低5至6毫米汞柱，其中风几率可降低35%至40%，冠心病几率降低20%至25%。虽然高血压的治疗包括非药物治疗和药物治疗，但本文将探讨洛沙坦（科素亚），它属于最新一类抗高血压药物——血管紧张素II拮抗剂。
