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前庭神经切断术、内淋巴乳突分流术及药物治疗后长期听力结果的比较。

Comparison of long-term hearing results after vestibular neurectomy, endolymphatic mastoid shunt, and medical therapy.

作者信息

Quaranta A, Onofri M, Sallustio V, Iurato S

机构信息

Department of Ophthalmology and Otolaryngology, University of Bari, Italy.

出版信息

Am J Otol. 1997 Jul;18(4):444-8.

PMID:9233483
Abstract

OBJECTIVE

This study aimed to compare the hearing changes in the long term after vestibular neurectomy, endolymphatic mastoid shunt, and medical treatment in classic Meniere's disease.

STUDY DESIGN

A retrospective case review was conducted based on audiologic follow-up between 5 and 21 years.

SETTING

The study was performed at two centers in Bari University Hospital, one performing vestibular neurectomy as the first surgical procedure for Meinere's disease and the other, endolymphatic mastoid shunt.

PATIENTS AND INTERVENTIONS

Of 68 patients with intractable idiopathic Meniere's disease, 29 underwent middle fossa vestibular neurectomy, and 17 had endolymphatic mastoid shunt; 22 were offered surgery but declined.

MAIN OUTCOME MEASURES

Outcome measures were puretone average (PTA), speech reception threshold, and speech discrimination score before and after treatment.

RESULTS

PTA declined by an average of 9.3 dB in neurectomy patients, 13.3 dB in patients undergoing endolymphatic mastoid shunt, and 18.1 dB in patients who were offered surgery but declined. Patients were subdivided into two cohorts based on their preoperative or initial PTA. In the patients who had PTA scores worse than 50 dB initially, the PTA declined an average of 4.3 dB in the vestibular neurectomy group, 11.5 dB in the endolymphatic sac group, and 4 dB in the nonsurgical group. In the patients with PTA > or = 50 dB initially, the PTA declined an average of of 25.3 dB in the vestibular neurectomy group, 16.1 in the endolymphatic sac group, and 26.2 dB in the nonsurgical group. Although shunt patients with good hearing initially deteriorated less than neurectomy patients and less than patients who declined surgery, the difference was not significant.

CONCLUSIONS

These results indicate that patients with poor hearing stabilized, while patients with good hearing continued to deteriorate. The same conditions were observed in the patients who had surgery and those who were offered surgery but declined.

摘要

目的

本研究旨在比较前庭神经切断术、内淋巴囊乳突分流术及药物治疗经典梅尼埃病后的长期听力变化。

研究设计

基于5至21年的听力随访进行回顾性病例分析。

研究地点

研究在巴里大学医院的两个中心进行,其中一个中心将前庭神经切断术作为梅尼埃病的首选手术方式,另一个中心则进行内淋巴囊乳突分流术。

患者与干预措施

68例难治性特发性梅尼埃病患者中,29例行中颅窝前庭神经切断术,17例行内淋巴囊乳突分流术;22例患者被建议手术,但拒绝了。

主要观察指标

观察指标为治疗前后的纯音平均听阈(PTA)、言语接受阈及言语辨别得分。

结果

神经切断术患者的PTA平均下降9.3 dB,内淋巴囊乳突分流术患者下降13.3 dB,被建议手术但拒绝的患者下降18.1 dB。根据术前或初始PTA将患者分为两组。初始PTA评分高于50 dB的患者中,前庭神经切断术组PTA平均下降25.3 dB,内淋巴囊组下降16.1 dB,非手术组下降26.2 dB。初始PTA评分低于50 dB的患者中,前庭神经切断术组PTA平均下降4.3 dB,内淋巴囊组下降11.5 dB,非手术组下降4 dB。虽然初始听力较好的分流术患者听力恶化程度低于神经切断术患者及拒绝手术的患者,但差异无统计学意义。

结论

这些结果表明,听力较差的患者听力趋于稳定,而听力较好的患者听力持续恶化。手术患者与被建议手术但拒绝的患者情况相同。

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