Pytel' Iu A, Aliaev Iu G
Khirurgiia (Mosk). 1997(3):29-35.
Intravenous tumor invasion occurred in 84 out of 600 patients who had been operated on for carcinoma of the kidney. The inferior vena cava was thrombosed by a tumor in 54 patients. Ultrasonic examination, computed tomography, and venocavography were used in establishing the diagnosis of intravenous invasion. It is stressed that information on the upper border of the thrombus in the inferior vena cava must be obtained before the operation, and that in block on the inferior cavogram transatrial venocavography is absolutely indicated. The presence of absence of growth of intracaval tumor masses into the wall of the inferior vena cava is an important moment determining peculiarities of the operation. In the authors experience such invasion was encountered in 30% of patients. Fifty-two patients had subdiaphragmatic thrombosis of the inferior vena cava and 2 patients had supradiaphragmatic thrombosis. In addition to radical nephrectomy, 28 patients underwent resection of the lateral surface of vena cava inferior, 17--thrombectomy from vena cava inferior, and 8--resection of a segment of this vein. Postoperative lethality was 9.5%, 5-year survival was 40.8%. It was found that venous invasion without growth of the tumor into the fibrous capsule of the kidney and without lymphogenous and distant metastases has no negative effect on the prognosis if the tumor masses had been removed completely from vena cava inferior. The authors believe operations on patients with renal carcinoma and venous tumor invasion in stages T2N0M0, T3N0M0 and T2-3N1-2M0 to be advisable.
600例接受肾细胞癌手术的患者中,84例发生静脉内肿瘤侵犯。54例患者的下腔静脉被肿瘤血栓形成。超声检查、计算机断层扫描和静脉造影用于确定静脉侵犯的诊断。强调在手术前必须获得下腔静脉血栓上缘的信息,并且在静脉造影显示阻塞时,绝对需要进行经心房静脉造影。下腔静脉内肿瘤肿块是否侵入下腔静脉壁是决定手术特点的重要因素。根据作者的经验,30%的患者出现这种侵犯。52例患者下腔静脉有膈下血栓形成,2例有膈上血栓形成。除根治性肾切除术外,28例患者接受下腔静脉外侧表面切除术,17例接受下腔静脉血栓切除术,8例接受该静脉段切除术。术后死亡率为9.5%,5年生存率为40.8%。研究发现,如果肿瘤肿块已从下腔静脉完全清除,静脉侵犯但肿瘤未侵入肾纤维囊且无淋巴源性和远处转移对预后无负面影响。作者认为,对处于T2N0M0、T3N0M0和T2 - 3N1 - 2M0期的肾癌和静脉肿瘤侵犯患者进行手术是可取的。