Drogset J O, Haaverstad R, Levang O W, Dalaker M, Bjerkeset T
Kirurgisk klinikk, Regionsykehuset i Trondheim.
Tidsskr Nor Laegeforen. 1997 Jun 10;117(15):2177-8.
During the period 1977-95, 20 patients underwent surgery for carcinoid tumour in the bronchus at the University Hospital of Trondheim (n = 16) and Innherred County Hospital (n = 4). All the tumours were typical carcinoid tumours. Median age of the patients was 41 years (range 16-78 years). The observation period averaged 7.5 years (0.5-18 years). The most common symptoms were cough, dyspnoea, wheezing and pneumonia. One patient had carcinoid syndrome. Chest X-ray were negative in three of the patients. Bronchoscopy was carried out in all the patients. Biopsies were taken in ten of them, and the diagnosis was conclusive in five cases. Lateral thoracotomy was performed in all the patients. The surgical procedures were lobectomy (15), segmental/wedge resection (3), bronchotomy with tumour resection (1) and sleeve resection (1). 19 patients were still alive at the time of follow-up, with no tumour recurrence. One patient died from cerebral stroke eight years after surgery. Good long-term results were found, and the study supports the use of limited lung resection or bronchoplasty operations to treat carcinoid tumour in the bronchus if the primary tumour is localised and there are no metastases.
1977年至1995年期间,20例患者在特隆赫姆大学医院(16例)和因内黑德郡医院(4例)接受了支气管类癌肿瘤手术。所有肿瘤均为典型类癌肿瘤。患者的中位年龄为41岁(范围16 - 78岁)。观察期平均为7.5年(0.5 - 18年)。最常见的症状是咳嗽、呼吸困难、喘息和肺炎。1例患者出现类癌综合征。3例患者胸部X线检查结果为阴性。所有患者均接受了支气管镜检查。其中10例患者进行了活检,5例确诊。所有患者均接受了侧开胸手术。手术方式包括肺叶切除术(15例)、节段性/楔形切除术(3例)、肿瘤切除支气管切开术(1例)和袖状切除术(1例)。随访时19例患者仍存活,无肿瘤复发。1例患者术后8年死于脑卒中。研究发现长期效果良好,该研究支持对于局限性原发性肿瘤且无转移的支气管类癌肿瘤,采用有限肺切除术或支气管成形术进行治疗。