短暂性全面性遗忘症中的情绪唤起与恐惧症

Emotional arousal and phobia in transient global amnesia.

作者信息

Inzitari D, Pantoni L, Lamassa M, Pallanti S, Pracucci G, Marini P

机构信息

Department of Neurological and Psychiatric Sciences, University of Florence, Italy.

出版信息

Arch Neurol. 1997 Jul;54(7):866-73. doi: 10.1001/archneur.1997.00550190056015.

DOI:10.1001/archneur.1997.00550190056015

PMID:9236576

Abstract

OBJECTIVE

To evaluate the role of emotionally stressful or phobogenic events and phobic personality traits in transient global amnesia (TGA).

DESIGN

Case-control study.

SETTING

Tertiary care center.

PATIENTS

Fifty-one case patients with TGA (mean +/- SD age, 62.7 +/- 6.7 years) compared with 51 control patients with transient ischemic attacks (mean +/- SD age, 63.8 +/- 6.7 years).

MAIN OUTCOME MEASURES

Precipitant factors, life events, and phobic attitudes.

RESULTS

Of the 25 TGA attacks that were triggered by a precipitant, 11 were possibly related to emotionally stressful or phobogenic situations. On a scale that measured phobic attitudes, the case patients with TGA scored significantly higher than the control patients with transient ischemic attacks (mean +/- SD total score, 15.21 +/- 11.0 vs 4.41 +/- 5.2; P < .001 by corrected analysis of variance for age, sex, and education). The amount of stressful live events in the year that preceded the attack did not differ between the case patients with TGA and the control patients with transient ischemic attacks.

CONCLUSION

The results support the hypothesis that emotional arousal and phobia are involved in TGA.

摘要

目的

评估情绪应激或致恐惧事件及恐惧性人格特质在短暂性全面性遗忘症（TGA）中的作用。

设计

病例对照研究。

地点

三级医疗中心。

患者

51例TGA患者（平均±标准差年龄，62.7±6.7岁）与51例短暂性脑缺血发作对照患者（平均±标准差年龄，63.8±6.7岁）。

主要观察指标

诱发因素、生活事件及恐惧态度。

结果

在由诱发因素引发的25次TGA发作中，11次可能与情绪应激或致恐惧情况有关。在一项测量恐惧态度的量表上，TGA病例患者的得分显著高于短暂性脑缺血发作对照患者（平均±标准差总分，15.21±11.0对4.41±5.2；经年龄、性别和教育程度校正的方差分析，P<.001）。TGA病例患者与短暂性脑缺血发作对照患者在发作前一年的应激性生活事件数量无差异。