Krygier G, Amado A, Salisbury S, Fernandez I, Maedo N, Vazquez T
Radiotherapeutical and Clinical Oncology Services of the Hospital de Clínicas, School of Medicine, Montevideo, Uruguay.
Lung Cancer. 1997 Jul;17(2-3):271-5. doi: 10.1016/s0169-5002(97)00030-5.
Liposarcoma of the lung is extremely rare with only 11 cases previously reported. A case of a locally advanced pulmonary pleomorphic liposarcoma in a 49-year-old male is presented. Surgery was performed but radical resection was not possible. Post-operative radiotherapy (40 Gy) was given concurrently with cisplatin (12.5 mg daily for 10 days). A partial response of short duration was obtained. The patient died 8 months following surgery with disseminated disease. Based on reports in the literature, liposarcoma of the lung must be classified as an aggressive highly metastatic disease responding poorly to both chemotherapy and radiotherapy.
肺脂肪肉瘤极为罕见，此前仅有11例报道。本文报告一例49岁男性的局部晚期肺多形性脂肪肉瘤病例。患者接受了手术，但无法进行根治性切除。术后放疗（40 Gy）与顺铂（每日12.5 mg，共10天）同步进行。获得了短期的部分缓解。患者术后8个月因疾病播散死亡。根据文献报道，肺脂肪肉瘤必须归类为侵袭性高转移性疾病，对化疗和放疗反应均较差。
