Severin E, Sartore S, Schiaffino S
Experientia. 1977 Nov 15;33(11):1489. doi: 10.1007/BF01918826.
Isoproterenol at relatively high doses (2.5 mg/ml) has a marked toxic effect on rat heart muscle cells cultivated in vitro. This effect is not prevented by propranolol and therefore is not mediated by beta adrenergic receptors.
相对高剂量(2.5毫克/毫升)的异丙肾上腺素对体外培养的大鼠心肌细胞有明显的毒性作用。普萘洛尔不能预防这种作用,因此它不是由β肾上腺素能受体介导的。