伴刀豆球蛋白A体外诱导犬甲状腺滤泡细胞的超微结构变化。
Ultrastructural changes in dog thyroid follicular cells elicit by concanavalin A in vitro.
作者信息
Fernandez-Pol J A, Binette J P, Hays M T
出版信息
Experientia. 1977 Nov 15;33(11):1493-5. doi: 10.1007/BF01918829.
PMID:923722
Abstract
Dog thyroid follicular cells exposed to concanavalin A (Con A) in vitro showed changes in cell shape, induction of colloid droplets and alterations in the distribution of microvilli. Cells exposed to Con A plus suboptimal concentrations of TSH (thyroid stimulating hormone) showed pseudopods and their cytoplasm was virtually occupied with colloid droplets. This findings suggest that Con A potentiated pseudopod and colloid droplet formation induced by TSH.
摘要
体外暴露于伴刀豆球蛋白A（Con A）的犬甲状腺滤泡细胞呈现出细胞形态变化、胶体小滴的诱导以及微绒毛分布的改变。暴露于Con A加次优浓度促甲状腺激素（TSH）的细胞显示出伪足，并且它们的细胞质几乎被胶体小滴占据。这些发现表明Con A增强了TSH诱导的伪足和胶体小滴形成。
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