• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Selenite nuclear cataract: review of the model.

作者信息

Shearer T R, Ma H, Fukiage C, Azuma M

机构信息

Department of Oral Molecular Biology, Oregon Health Sciences University, Portland, OR 97201, USA.

出版信息

Mol Vis. 1997 Jul 23;3:8.

PMID:9238097
Abstract

Selenite overdose cataract, an experimental model of nuclear cataract produced in young rats is reviewed. Topics include procedures for cataract production and assessment, metabolic and molecular changes in the epithelium of the lens, calcium accumulation, activation of calcium-activated protease system, mechanisms for crystallin precipitation, anti-cataract drug testing and relevance to human cataract.

摘要

相似文献

1
Selenite nuclear cataract: review of the model.
Mol Vis. 1997 Jul 23;3:8.
2
Changes in calpain II mRNA in young rat lens during maturation and cataract formation.幼鼠晶状体在成熟和白内障形成过程中钙蛋白酶II信使核糖核酸的变化
Exp Eye Res. 1997 Mar;64(3):437-45. doi: 10.1006/exer.1996.0229.
3
Calpains: targets of cataract prevention?钙蛋白酶:预防白内障的靶点?
Trends Mol Med. 2004 Feb;10(2):78-84. doi: 10.1016/j.molmed.2003.12.007.
4
Regional distribution of free calcium in selenite cataract: relation to calpain II.亚硒酸盐性白内障中游离钙的区域分布:与钙蛋白酶II的关系
Invest Ophthalmol Vis Sci. 1987 Oct;28(10):1702-6.
5
Biochemical changes in selenite cataract model measured by high-resolution MAS H NMR spectroscopy.通过高分辨率魔角旋转核磁共振光谱法测定亚硒酸盐白内障模型中的生化变化。
Acta Ophthalmol Scand. 2006 Oct;84(5):684-92. doi: 10.1111/j.1600-0420.2006.00716.x.
6
Calpains: enzymes of vision?钙蛋白酶:视觉相关的酶?
Med Sci Monit. 2005 Sep;11(9):RA301-10. Epub 2005 Aug 26.
7
Vitex negundo attenuates calpain activation and cataractogenesis in selenite models.黄荆可减轻亚硒酸盐模型中的钙蛋白酶激活和白内障形成。
Exp Eye Res. 2009 Mar;88(3):575-82. doi: 10.1016/j.exer.2008.11.020. Epub 2008 Dec 6.
8
The effect of acetyl-L-carnitine on lenticular calpain activity in prevention of selenite-induced cataractogenesis.乙酰左旋肉碱对晶状体钙蛋白酶活性在预防亚硒酸盐诱导的白内障形成中的作用。
Exp Eye Res. 2009 May;88(5):938-44. doi: 10.1016/j.exer.2008.12.009. Epub 2008 Dec 30.
9
Evidence for apoptosis in the selenite rat model of cataract.亚硒酸盐诱导的大鼠白内障模型中细胞凋亡的证据。
Biochem Biophys Res Commun. 2000 Aug 28;275(2):300-6. doi: 10.1006/bbrc.2000.3298.
10
Selenite cataract and its attenuation by vitamin-E in Wistar rats.亚硒酸盐诱导的白内障及其在Wistar大鼠中维生素E的减轻作用
Indian J Ophthalmol. 2003 Dec;51(4):365-6; author reply 366.

引用本文的文献

1
Endoplasmic reticulum stress involved in age-related nuclear cataract induced by sodium selenite.内质网应激参与亚硒酸钠诱导的年龄相关性核性白内障的发生。
Sci Rep. 2025 Jul 1;15(1):22227. doi: 10.1038/s41598-025-07745-5.
2
Minimizing Oxidative Stress in the Lens: Alternative Measures for Elevating Glutathione in the Lens to Protect against Cataract.减轻晶状体中的氧化应激:提高晶状体中谷胱甘肽以预防白内障的替代措施
Antioxidants (Basel). 2024 Oct 1;13(10):1193. doi: 10.3390/antiox13101193.
3
The impact of lutein-loaded poly(lactic-co-glycolic acid) nanoparticles following topical application: An in vitro and in vivo study.
局部应用负载叶黄素的聚乳酸-羟基乙酸共聚物纳米颗粒的影响:一项体外和体内研究。
PLoS One. 2024 Aug 1;19(8):e0306640. doi: 10.1371/journal.pone.0306640. eCollection 2024.
4
Transcriptome sequencing and microRNA-mRNA regulatory network construction in the lens from a NaSeO-induced Sprague Dawley rat cataract model.基于 NaSeO 诱导的 Sprague Dawley 大鼠白内障模型的晶状体转录组测序和 miRNA-mRNA 调控网络构建。
BMC Ophthalmol. 2023 Nov 16;23(1):461. doi: 10.1186/s12886-023-03202-x.
5
Lens-specific βA3/A1-conditional knockout mice: Phenotypic characteristics and calpain activation causing protein degradation and insolubilization.晶状体特异性βA3/A1-条件性基因敲除小鼠:表型特征和钙蛋白酶激活导致蛋白降解和不溶性。
PLoS One. 2023 Mar 29;18(3):e0281386. doi: 10.1371/journal.pone.0281386. eCollection 2023.
6
Selenium intake help prevent age-related cataract formation: Evidence from NHANES 2001-2008.摄入硒有助于预防与年龄相关的白内障形成:来自2001 - 2008年美国国家健康与营养检查调查(NHANES)的证据。
Front Nutr. 2023 Jan 27;10:1042893. doi: 10.3389/fnut.2023.1042893. eCollection 2023.
7
Loss of fiber cell communication may contribute to the development of cataracts of many different etiologies.纤维细胞通讯的丧失可能导致多种不同病因的白内障的发生。
Front Physiol. 2022 Sep 12;13:989524. doi: 10.3389/fphys.2022.989524. eCollection 2022.
8
Deficiency of Jamc Leads to Congenital Nuclear Cataract and Activates the Unfolded Protein Response in Mouse Lenses.Jamc 缺乏导致先天性核白内障,并激活小鼠晶状体中的未折叠蛋白反应。
Invest Ophthalmol Vis Sci. 2022 Sep 1;63(10):1. doi: 10.1167/iovs.63.10.1.
9
Combination of Lanosterol and Nilvadipine Nanosuspensions Rescues Lens Opacification in Selenite-Induced Cataractic Rats.羊毛甾醇与尼伐地平纳米混悬液联合用药可缓解亚硒酸盐诱导的白内障大鼠的晶状体混浊
Pharmaceutics. 2022 Jul 21;14(7):1520. doi: 10.3390/pharmaceutics14071520.
10
Instillation of Ophthalmic Formulation Containing Nilvadipine Nanocrystals Attenuates Lens Opacification in Shumiya Cataract Rats.含有尼伐地平纳米晶体的眼科制剂滴眼可减轻舒米亚白内障大鼠的晶状体混浊。
Pharmaceutics. 2021 Nov 25;13(12):1999. doi: 10.3390/pharmaceutics13121999.