Shearer T R, Ma H, Fukiage C, Azuma M
Department of Oral Molecular Biology, Oregon Health Sciences University, Portland, OR 97201, USA.
Mol Vis. 1997 Jul 23;3:8.
Selenite overdose cataract, an experimental model of nuclear cataract produced in young rats is reviewed. Topics include procedures for cataract production and assessment, metabolic and molecular changes in the epithelium of the lens, calcium accumulation, activation of calcium-activated protease system, mechanisms for crystallin precipitation, anti-cataract drug testing and relevance to human cataract.