Nazeyrollas P, Metz D, Maillier B, Jennesseaux C, Maes D, Tassan S, Jolly D, Chabert J P, Chapoutot L, Elaerts J
Service de cardiologie, Centre hospitalier universitaire de Reims.
Arch Mal Coeur Vaiss. 1997 Apr;90(4):463-9.
The diagnostic value of transthoracic echocardiography in acute pulmonary embolism is not well established. Although many parameters are abnormal, the thresholds used vary according to the authors, limiting the contribution of the investigation to the diagnosis. In a prospective study of 70 patients with suspected acute pulmonary embolism without previous cardio-respiratory disease, the authors tried to determine the diagnostic thresholds using discriminating linear analysis and ROC curves. Parameters easily recorded in an emergency were analysed: end diastolic ventricular dimensions, ratio of these diameters and maximal velocity of tricuspid regurgitant flow. Thirty-one patients had pulmonary embolism quantified by the Miller index (average: 16 +/- 7, range 2 to 28). Measurements of left ventricular dimension were disappointing (sensitivity: 0.52, specificity: 0.73 for a threshold value of 45 mm). The right ventricular dimension was a better predictive parameter (sensitivity: 0.70, specificity: 0.86 for a threshold value of 25 mm). However, the ratio of right to left ventricular dimension had a better diagnostic value (sensitivity: 0.85, specificity: 0.78 for a threshold value of 0.5). The best diagnostic parameter was the maximal velocity of tricuspid regurgitation (sensitivity: 0.93, specificity: 0.82 for a threshold value of 2.5 m/s). The authors conclude that the maximal velocity of tricuspid regurgitation with a threshold of 2.5 m/s and the ratio of the ventricular dimensions with a threshold value of 0.5 are valuable diagnostic indicators for acute pulmonary embolism.
经胸超声心动图在急性肺栓塞中的诊断价值尚未明确。尽管许多参数异常,但不同作者所采用的阈值各不相同,这限制了该检查对诊断的贡献。在一项针对70例疑似急性肺栓塞且无既往心肺疾病患者的前瞻性研究中,作者试图通过判别线性分析和ROC曲线来确定诊断阈值。分析了在急诊中易于记录的参数:舒张末期心室尺寸、这些直径的比值以及三尖瓣反流的最大流速。31例患者的肺栓塞通过米勒指数进行量化(平均值:16±7,范围2至28)。左心室尺寸的测量结果令人失望(对于45毫米的阈值,敏感性:0.52,特异性:0.73)。右心室尺寸是一个更好的预测参数(对于25毫米的阈值,敏感性:0.70,特异性:0.86)。然而,右心室与左心室尺寸的比值具有更好的诊断价值(对于0.5的阈值,敏感性:0.85,特异性:0.78)。最佳诊断参数是三尖瓣反流的最大流速(对于2.5米/秒的阈值,敏感性:0.93,特异性:0.82)。作者得出结论,三尖瓣反流最大流速阈值为2.5米/秒以及心室尺寸比值阈值为0.5是急性肺栓塞有价值的诊断指标。