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高分辨率探头超声引导下乳腺疾病细针穿刺细胞学研究

Study on ultrasonically guided fine-needle aspiration cytology for breast disorders with high-resolution transducer.

作者信息

Kubota M

机构信息

Department of Surgery 2, School of Medicine, Tokai University, Kanagawa, Japan.

出版信息

Tokai J Exp Clin Med. 1996 Feb;21(1):7-12.

PMID:9239798
Abstract

The author participated in the development annular array transducer. The author used this new device in 147 patients (aged 43.4 years ranging from 21 to 81 years) and ultrasonically detected 193 breast lesions including 126 nonpalpable ones (65.3%). After that, the author performed 234 punctures for aspiration cytology using the same device and 22 gauge needle. The needle tip was intralesionally identified in 174 of the 234 punctures (74.4%) and 146 of the 193 lesions (75.6%). The sensitivity, specificity and accuracy of cytological diagnosis were 72.7% (8/11), 91.2% (31/34) and 86.7% (39/45), respectively. No cell could be aspirated in 61 of the 146 lesions (41.8%). These results were comparable to those obtained from the conventional devices. Annular array transducer will increase the frequency of ultrasonic detection of small breast lesions. Fine needle aspiration cytology under ultrasonic guide with this new device will efficiently and speedily rule out malignant lesions and facilitate management of benign lesions at the outpatient department. This study suggests that ultrasonically malignant lesions should immediately be examined histologically without undergoing cytological examination. It should be noted that some cystic lesions are concentrated and accompanied by positive internal echoes. These cystic lesions show a change in size on the ultrasonic image after aspiration and contain paste- or gruel-like material.

摘要

作者参与了环形阵列换能器的研发。作者将这一新设备应用于147例患者(年龄43.4岁,范围为21至81岁),超声检测到193个乳腺病变,其中包括126个不可触及的病变(65.3%)。之后,作者使用同一设备和22号针进行了234次穿刺抽吸细胞学检查。在234次穿刺中有174次(74.4%)、在193个病变中有146个(75.6%)确定针尖位于病变内。细胞学诊断的敏感性、特异性和准确性分别为72.7%(8/11)、91.2%(31/34)和86.7%(39/45)。在146个病变中有61个(41.8%)无法吸出细胞。这些结果与使用传统设备所获得的结果相当。环形阵列换能器将提高乳腺小病变的超声检测频率。使用这一新设备在超声引导下进行细针抽吸细胞学检查将有效且快速地排除恶性病变,并便于在门诊对良性病变进行处理。本研究表明,超声检查为恶性的病变应立即进行组织学检查,而无需进行细胞学检查。应当注意的是,一些囊性病变较为密集并伴有内部回声阳性。这些囊性病变在抽吸后超声图像上显示大小改变,并含有糊状或粥样物质。

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