Chaisiri K, Pongpaew P, Tungtrongchitr R, Phonrat B, Kulleap S, Kuhathong C, Sutthiwong P, Intarakhao C, Mahaweerawat U, Khongdee W, Sanchaisuriya P, Saowakontha S, Merkle A, Schelp F P
Khon Kaen Provincial Health Office, Thailand.
J Med Assoc Thai. 1997 Jun;80(6):363-71.
Three hundred and fifty-five individuals, 152 males and 203 females, aged between 30 and 74 years, were randomly selected in a two stage selection process from rural communities in three districts of Khon Kaen Province, Northeast Thailand. The prevalence of impaired glucose tolerance (IGT) and non-insulin dependent diabetes mellitus (NIDDM) in the rural area of Northeast Thailand were measured. In addition, the validity of the urine stick and fasting blood sugar as screening tools against the two hours glucose loading test as golden standard were determined. The survey was conducted in July 1995. The glucose loading test was performed on 277 individuals. IGT and NIDDM were classified according to current World Health Organization suggestions. Prevalence rates for IGT were 18.1 per cent and for NIDDM 11.9 per cent. No difference was found between males and females, also when controlled for age. NIDDM prevalence increased with age but IGT rates already were high in the younger age groups. This finding suggests that IGT precedes NIDDM in Thailand. The validity of the urine stick as a screening tool in communities was insufficient, with a sensitivity of less than 20 per cent. When using fasting blood sugar as a screening test, the sensitivity was close to 44 per cent and the specificity 90 per cent. It is concluded that the urine stick is not a useful screening tool and the method of using blood sugar concentrations for screening have to be improved before it can be applied within communities.
在泰国东北部孔敬府三个地区的农村社区，通过两阶段抽样程序随机选取了355人，其中男性152人，女性203人，年龄在30至74岁之间。对泰国东北部农村地区糖耐量受损（IGT）和非胰岛素依赖型糖尿病（NIDDM）的患病率进行了测量。此外，以两小时葡萄糖耐量试验作为金标准，确定了尿糖试纸和空腹血糖作为筛查工具的有效性。该调查于1995年7月进行。对277人进行了葡萄糖耐量试验。IGT和NIDDM根据世界卫生组织当前的建议进行分类。IGT的患病率为18.1%，NIDDM的患病率为11.9%。男性和女性之间未发现差异，年龄校正后也是如此。NIDDM患病率随年龄增加，但IGT患病率在较年轻年龄组中就已经很高。这一发现表明，在泰国IGT先于NIDDM出现。尿糖试纸作为社区筛查工具的有效性不足，灵敏度低于20%。当使用空腹血糖作为筛查试验时，灵敏度接近44%，特异性为90%。结论是，尿糖试纸不是一种有用的筛查工具，在社区应用之前，利用血糖浓度进行筛查的方法必须改进。
