Di Summa M, Albiero R, Carletta C, Del Giglio A, Trevi G P, Morea M
G Ital Cardiol. 1977;7(11):1093-7.
In this study we present the results of 5-years Follow-up of Clinical experimentation with biological prostheses of Hancock in 250 patients underwent a valvular replacement at the Cardiovascular Surgery Institute of Padua University in Verona. We report the immediate and long-term results with the death causes and the complications related above all with thrombo-embolic events. For such complications it was done a comparison relatively to the cases with mitral and aortic prostheses, with the results obtained from another Cardiovascular Surgery Center where are always applied artificial prostheses. From this comparison results that Hancock's biological prostheses has a major tendency to give incidence of embolic in the first months following the valvular replacement, but successively it is clearly to be prefered to artificial prostheses.
在本研究中，我们呈现了对250例在维罗纳帕多瓦大学心血管外科研究所接受瓣膜置换术并使用汉考克生物假体进行临床实验的患者进行5年随访的结果。我们报告了即时和长期结果，包括死亡原因以及尤其是与血栓栓塞事件相关的并发症。针对这些并发症，我们与二尖瓣和主动脉假体病例进行了比较，并与另一个一直使用人工假体的心血管外科中心所获得的结果进行了比较。从该比较结果来看，汉考克生物假体在瓣膜置换后的头几个月有较高的栓塞发生率倾向，但随后明显优于人工假体。
