Bodis-Wollner I
Department of Neurology, State University, SUNY-HSCB, Brooklyn 11203, USA.
Clin Electroencephalogr. 1997 Jul;28(3):143-7. doi: 10.1177/155005949702800305.
A retinal dopaminergic deficiency underlies some visual changes in Parkinson's disease (PD), in particular those elicited by stimuli near the peak of the human and monkey spatial contrast sensitivity. The correspondence of retinal changes and VEP alterations is not perfect: they do not seem to rely on identical mechanisms. It seems that additional pathology beyond the retina affects visual responses, including VEPs. The relevance of "distal" primary VEP changes to higher cognitive visual abnormalities in PD is not established at present.
视网膜多巴胺能缺乏是帕金森病（PD）某些视觉变化的基础，尤其是由接近人类和猴子空间对比敏感度峰值的刺激所引发的变化。视网膜变化与视觉诱发电位（VEP）改变之间的对应关系并不完美：它们似乎并不依赖于相同的机制。似乎视网膜以外的其他病理状况会影响视觉反应，包括VEP。目前尚不清楚PD中“远端”原发性VEP变化与更高层次认知性视觉异常之间的相关性。
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