Fortenberry J D, Orr D P, Katz B P, Brizendine E J, Blythe M J
Department of Pediatrics, Indiana University Medical School, Indianapolis, USA.
Sex Transm Dis. 1997 Jul;24(6):313-9. doi: 10.1097/00007435-199707000-00001.
To evaluate the potential causal relationship between alcohol and drug use and behavior that increases the risk of sexually transmitted diseases.
Longitudinal study conducted at a sexually transmitted diseases clinic and four community-based primary care clinics for adolescents. The participants were 82 female adolescents (age 16-19 years) who agreed to complete diaries recording each coital event. Subjects were participants in a larger study of prevention of reinfections by sexually transmitted organisms. The main outcome measure was condom use at each coital event. Predictor variables were usual pattern of condom use (when substances were not involved) and two event-specific measures: sex partner change and use of alcohol or drugs before intercourse.
Average time span of the diaries was 9.2 weeks. Subjects recorded 1,265 coital events. Ninety-three substance-associated coital events were recorded by 22 subjects. Event-specific condom use was associated with usual pattern of condom use, but not with event-specific variables of partner change or substance use before intercourse.
These data do not support the hypothesis that substance use causes alteration of adolescent women's behavior in a manner that increases risk of sexually transmitted diseases.
评估酒精和药物使用与增加性传播疾病风险的行为之间的潜在因果关系。
在一家性传播疾病诊所和四家社区青少年初级保健诊所进行的纵向研究。参与者为82名年龄在16至19岁之间的女性青少年，她们同意完成记录每次性交事件的日记。受试者参与了一项关于性传播病原体再感染预防的更大规模研究。主要结局指标是每次性交事件时的避孕套使用情况。预测变量为通常的避孕套使用模式（不涉及物质时）以及两项特定事件指标：性伴侣更换和性交前饮酒或使用药物情况。
日记的平均时长为9.2周。受试者记录了1265次性交事件。22名受试者记录了93次与物质相关的性交事件。特定事件的避孕套使用与通常的避孕套使用模式相关，但与性交前性伴侣更换或物质使用的特定事件变量无关。
这些数据不支持物质使用会以增加性传播疾病风险的方式导致青春期女性行为改变这一假设。
