Fenoglio J J, Diana D J, Bowen T E, McAllister H A, Ferrans V J
Hum Pathol. 1977 Nov;8(6):700-6. doi: 10.1016/s0046-8177(77)80099-3.
Electron microscopic study of a cardiac rhabdomyoma removed at open heart operation revealed large rounded or polygonal cells that contained large amounts of monoparticulate glycogen. Myofibrils in these cells were few and located either subjacent to the plasma membranes or radiating from central areas. Leptofibrils and masses of anomalous Z band material were abundant. Shallow tubular sarcolemmal invaginations and elements of free and junctional sarcoplasmic reticulum were associated with the myofibrils. Desmosomes and nexuses were evident in intercellular junctions, which were extensive and randomly distributed throughout the cell surfaces. It is concluded that cardiac rhabdomyomas probably are hamartomas.
对在心脏直视手术中切除的心脏横纹肌瘤进行电子显微镜研究发现，有大的圆形或多边形细胞，这些细胞含有大量单颗粒糖原。这些细胞中的肌原纤维很少，位于质膜下方或从中心区域呈放射状分布。细肌丝和大量异常Z带物质很丰富。浅的管状肌膜内陷以及游离和连接肌浆网成分与肌原纤维相关。在细胞间连接中可见桥粒和缝隙连接，它们广泛且随机地分布在整个细胞表面。结论是心脏横纹肌瘤可能是错构瘤。
