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[超致死剂量辐射下大型实验动物放射病临床表现的定量模式。犬放射病临床表现的定量模式]

[Quantitative patterns in the clinical manifestations of radiation sickness in large laboratory animals exposed to radiation at superlethal doses. The quantitative patterns in the manifestations of radiation sickness in dogs].

作者信息

Darenskaia N G, Korotkevich A O, Kuznetsova S S, Nasonova T A

出版信息

Radiats Biol Radioecol. 1997 May-Jun;37(3):423-30.

PMID:9244533
Abstract

Radiation sickness manifestations have been studied in dogs exposed to electrons (electron energy 25 MeV) and gamma-neutron radiation (neutron energies of 0.37 and 1.2 MeV) in a wide dose range. Dose-response relationships have been calculated for mortality and some clinical manifestations of the intestinal and cerebral forms of radiation sickness. With regard to mortality, the highest effect has been observed for gamma-neutron radiation with a neutron energy of 1.2 MeV. For equal physical doses and for those equally effective in relation to mortality, clinical manifestations of damage are more prominent following exposure to electrons.

摘要

在广泛的剂量范围内,对暴露于电子(电子能量为25兆电子伏)以及伽马 - 中子辐射(中子能量为0.37和1.2兆电子伏)的狗的放射病表现进行了研究。已经计算了放射病肠道型和脑型的死亡率及一些临床表现的剂量 - 反应关系。关于死亡率,在中子能量为1.2兆电子伏的伽马 - 中子辐射中观察到最高效应。对于相等的物理剂量以及那些在死亡率方面等效的剂量,暴露于电子后损伤的临床表现更为突出。

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