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[菌血症和败血症抗菌治疗疗效的快速微生物学控制]

[The rapid microbiological control of the efficacy of the antibacterial therapy of bacteremia and septicemia].

作者信息

Kotliarova G A, Lopatkin N A, Kondrat'eva E M, Perepanova T S

出版信息

Urol Nefrol (Mosk). 1997 May-Jun(3):8-13.

PMID:9245063
Abstract

No previous isolation of the agent on the media is needed in using a new microbiological express-method of automatic control over antibacterial therapy of bacteremia and septicemia. The method is efficient in determination of sensitivity to the drug of the whole heterogeneous population of bacteria. It does not predict efficacy of antibacterial therapy but states the presence or absence of the effect in vivo. The method is integral, evaluates antibacterial plasma titer suggesting adequate correction. The duration of the test is maximum 12 h that is 3-4 times less than other methods.

摘要

在使用一种新的微生物快速自动控制菌血症和败血症抗菌治疗的方法时,无需事先在培养基上分离病原体。该方法在测定整个异质细菌群体对药物的敏感性方面很有效。它不能预测抗菌治疗的疗效,但能表明体内是否有治疗效果。该方法是综合性的,可评估抗菌血浆滴度并建议进行适当校正。测试持续时间最长为12小时,比其他方法少3至4倍。

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