Shekarsarai H, Zlotta A R, Drowart A, Van Vooren J P, De Cock M, Pirson M, Palfliet K, Jurion F, Vanonckelen A, Simon J, Schulman C C, Huygen K
Département dUrologie, Hôpital Universitaire Erasme, Bruxelles, Belgique.
Acta Urol Belg. 1997 Mar;65(1):1-4.
Optimal duration of immunotherapy treatment by BCG for the prevention of recurrences of superficial bladder cancer is still unknown. We have studied the evolution and duration of the cellular immunity response at the peripheral level after BCG intravesical instillations. Our results show that immunity activation after BCG is of short duration and don't take more than 6 months. Our results support, strengthen and partially allow to explain the utility of maintenance treatment by BCG following 6-weekly instillations.
卡介苗免疫疗法预防浅表性膀胱癌复发的最佳疗程仍不明确。我们研究了卡介苗膀胱内灌注后外周水平细胞免疫反应的演变及持续时间。我们的结果显示，卡介苗免疫激活持续时间较短，不超过6个月。我们的结果支持、强化并部分解释了每6周灌注一次后进行卡介苗维持治疗的效用。
