生长激素对全垂体功能减退症患者脂肪肝的影响。
Effect of growth hormone on fatty liver in panhypopituitarism.
作者信息
Takano S, Kanzaki S, Sato M, Kubo T, Seino Y
机构信息
Department of Paediatrics, Okayama University Medical School, Japan.
出版信息
Arch Dis Child. 1997 Jun;76(6):537-8. doi: 10.1136/adc.76.6.537.
Abstract
A 17 year old boy was admitted because of short stature and hepatomegaly. He was diagnosed with panhypopituitarism and fatty liver. The fatty liver improved, not with hydrocortisone or levothyroxine treatment, but with growth hormone administration. The fatty liver in this patient was attributable to a growth hormone deficient state.
摘要
一名17岁男孩因身材矮小和肝肿大入院。他被诊断为全垂体功能减退症和脂肪肝。脂肪肝并非通过氢化可的松或左甲状腺素治疗得到改善，而是通过给予生长激素得到改善。该患者的脂肪肝归因于生长激素缺乏状态。
相似文献
1
Effect of growth hormone on fatty liver in panhypopituitarism.
Arch Dis Child. 1997 Jun;76(6):537-8. doi: 10.1136/adc.76.6.537.
2
Imperforate anus, bilateral hydronephrosis, bilateral undescended testes and pituitary hypoplasia: a variant of Hall-Pallister syndrome or a new syndrome.
Acta Paediatr. 1995 Nov;84(11):1322-4. doi: 10.1111/j.1651-2227.1995.tb13560.x.
3
Adult height exceeding target height in a patient with congenital panhypopituitarism diagnosed after the age of 25 years.
J Pediatr Endocrinol. 1994 Jul-Sep;7(3):269-72. doi: 10.1515/jpem.1994.7.3.269.
4
Hypopituitarism.
Curr Ther Endocrinol Metab. 1994;5:26-9.
5
Hypopituitarism and anemia: effect of replacement therapy with hydrocortisone and/or levothyroxine.
J Endocrinol Invest. 2005 Jun;28(6):528-33. doi: 10.1007/BF03347241.
6
[Pancytopenia and acquired factor IX deficiency in patient with Sheehan's syndrome].
Med Clin (Barc). 2006 Sep 23;127(11):439. doi: 10.1157/13092780.
7
Adult panhypopituitarism presenting as idiopathic growth hormone deficiency in childhood.
Acta Paediatr Scand. 1991 Feb;80(2):255-8. doi: 10.1111/j.1651-2227.1991.tb11844.x.
8
[Effect of growth hormone on the serum concentration of thyroid hormones and thyroxine-binding globulin in hypopituitarism].
Orv Hetil. 1981 Apr 12;122(15):883-5.
9
Plasma growth hormone, insulin, and glucagon responses to arginine infusion in children and adolescents with idiopathic short stature, isolated growth hormone deficiency, panhypopituitarism, and anorexia nervosa.
Pediatr Res. 1975 Sep;9(9):733-8. doi: 10.1203/00006450-197509000-00010.
10
Transient elevation of urinary catecholamine excretion and cholestatic liver disease in a neonate with hypopituitarism.
J Pediatr Gastroenterol Nutr. 1992 Feb;14(2):153-9. doi: 10.1097/00005176-199202000-00006.
引用本文的文献
1
Case report: Pediatric hepatopulmonary syndrome despite strict weight control after craniopharyngioma surgery.
Front Endocrinol (Lausanne). 2024 Oct 30;15:1459451. doi: 10.3389/fendo.2024.1459451. eCollection 2024.
2
The Unexpected Detection of Esophageal Varices Caused by Liver Cirrhosis in a 47-Year-Old Man Treated with a Growth Hormone in Childhood.
Diseases. 2024 Oct 12;12(10):251. doi: 10.3390/diseases12100251.
3
Pituitary stalk interruption syndrome and liver cirrhosis associated with diabetes and an inactivating gene mutation: a case report and literature review.
Front Endocrinol (Lausanne). 2023 Dec 13;14:1297146. doi: 10.3389/fendo.2023.1297146. eCollection 2023.
4
Long-term Outcome of Body Composition, Ectopic Lipid, and Insulin Resistance Changes With Surgical Treatment of Acromegaly.
J Endocr Soc. 2023 Feb 21;7(5):bvad028. doi: 10.1210/jendso/bvad028. eCollection 2023 Mar 6.
5
Nonalcoholic fatty liver disease and non-liver comorbidities.
Clin Mol Hepatol. 2023 Feb;29(Suppl):s86-s102. doi: 10.3350/cmh.2022.0442. Epub 2023 Jan 5.
6
The acromegaly lipodystrophy.
Front Endocrinol (Lausanne). 2022 Sep 13;13:933039. doi: 10.3389/fendo.2022.933039. eCollection 2022.
7
Growth hormone deficiency and NAFLD: An overlooked and underrecognized link.
Hepatol Commun. 2022 Sep;6(9):2227-2237. doi: 10.1002/hep4.1953. Epub 2022 Jun 28.
8
Nonalcoholic Fatty Liver Disease and Endocrine Axes-A Scoping Review.
Metabolites. 2022 Mar 29;12(4):298. doi: 10.3390/metabo12040298.
9
Body Composition Changes with Long-term Pegvisomant Therapy of Acromegaly.
J Endocr Soc. 2021 Feb 1;5(3):bvab004. doi: 10.1210/jendso/bvab004. eCollection 2021 Mar 1.
10
A Case of Hypopituitarism Complicated by Non-Alcoholic Steatohepatitis and Severe Pulmonary Hypertension.
Am J Case Rep. 2021 Jan 4;22:e928004. doi: 10.12659/AJCR.928004.
本文引用的文献
1
In vitro effects of growth hormone in adipose tissue.
Acta Paediatr Suppl. 1994 Dec;406:48-53. doi: 10.1111/j.1651-2227.1994.tb13422.x.
2
Metabolic effects of growth hormone in children.
Metabolism. 1995 Oct;44(10 Suppl 4):97-102. doi: 10.1016/0026-0495(95)90228-7.
3
The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency.
N Engl J Med. 1989 Dec 28;321(26):1797-803. doi: 10.1056/NEJM198912283212605.
4
Effects of systemic growth hormone (GH) administration on regional adipose tissue distribution and metabolism in GH-deficient children.
J Clin Endocrinol Metab. 1989 Dec;69(6):1274-81. doi: 10.1210/jcem-69-6-1274.
5
Effects of insulin-like growth factor on linear growth, head circumference, and body fat in patients with Laron-type dwarfism.
Lancet. 1992 May 23;339(8804):1258-61. doi: 10.1016/0140-6736(92)91594-x.
6
Mechanisms for differences in lipolysis between human subcutaneous and omental fat cells.
J Clin Endocrinol Metab. 1992 Jul;75(1):15-20. doi: 10.1210/jcem.75.1.1320047.
Zotero 插件