Comer M, Kaushik N C
Department of Ophthalmology, Wrexham Maetor NHS Trust Hospital, Clwyd, UK.
Eye (Lond). 1997;11 ( Pt 1):115-7. doi: 10.1038/eye.1997.23.
Activated Protein C resistance is a recently described clotting disorder, accounting for several previously undiagnosed thrombophilic states. Initially this defect had been associated with leg vein thromboses, but it is now recognised that other vascular beds are also prone to clotting in this disorder. We report a case of acute proptosis in a patient with Activated Protein C resistance, due to cavernous sinus thrombosis.
活化蛋白C抵抗是一种最近才被描述的凝血障碍，可解释几种先前未被诊断出的易栓症状态。最初，这种缺陷与腿部静脉血栓形成有关，但现在人们认识到，在这种疾病中其他血管床也容易发生凝血。我们报告一例因海绵窦血栓形成导致活化蛋白C抵抗患者出现急性眼球突出的病例。
