Court E A, Watson A D, Peaston A E
Department of Veterinary Clinical Sciences, University of Sydney, New South Wales.
Aust Vet J. 1997 Jun;75(6):424-7. doi: 10.1111/j.1751-0813.1997.tb14347.x.
To characterise epidemiological and clinical findings, and diagnostic procedures undertaken, in cats with lymphosarcoma at a veterinary teaching hospital.
Retrospective case study.
Hospital records were reviewed for 7159 cats, sick or healthy, examined during a 10-year period (1984 to 1994). Sixty cats with lymphosarcoma were identified and classified by anatomical location of the tumor. Data on breed, age, sex, clinical signs and diagnostic procedures were collated.
The prevalence of feline lymphosarcoma in the hospital population was 0.84%. Siamese cats appeared predisposed to lymphosarcoma but other purebreds were not. Males were somewhat overrepresented amongst affected cats. Similar numbers of cases (12 to 18) were seen in each of the four anatomic categories (multicentric, mediastinal, alimentary and extranodal). Cats with mediastinal lymphosarcoma were mostly young and Siamese. Clinical signs in affected cats were varied, usually multiple and often nonspecific. Two of 22 cases tested positive for feline leukaemia virus antigen in blood and 6 of 13 were positive for feline immunodeficiency virus antibody.
Extranodal lymphosarcoma seemed more prevalent in this study than reported elsewhere. Siamese cats in the study population may have had a genetic predisposition to lymphosarcoma. Limited evidence suggested feline leukaemia virus may be less important, and feline immunodeficiency virus more important, in the local population than indicated in overseas reports. Additional studies are needed to investigate breed predisposition and feline leukaemia virus and feline immunodeficiency virus status in Australian cats with lymphosarcoma.
描述一家兽医教学医院中患有淋巴肉瘤的猫的流行病学和临床特征以及所采用的诊断程序。
回顾性病例研究。
查阅了10年期间（1984年至1994年）检查的7159只患病或健康猫的医院记录。确定了60只患有淋巴肉瘤的猫，并根据肿瘤的解剖位置进行分类。整理了有关品种、年龄、性别、临床症状和诊断程序的数据。
医院猫群中猫淋巴肉瘤的患病率为0.84%。暹罗猫似乎易患淋巴肉瘤，但其他纯种猫则不然。患病猫中雄性略多。四个解剖类别（多中心型、纵隔型、消化道型和结外型）中的病例数相似（12至18例）。纵隔型淋巴肉瘤的猫大多为年轻暹罗猫。患病猫的临床症状多种多样，通常为多种症状且往往不具特异性。22例中有2例血液中猫白血病病毒抗原检测呈阳性，13例中有6例猫免疫缺陷病毒抗体呈阳性。
在本研究中，结外型淋巴肉瘤似乎比其他地方报道的更为普遍。研究群体中的暹罗猫可能对淋巴肉瘤有遗传易感性。有限的证据表明，在当地猫群中，猫白血病病毒可能不如海外报道中那么重要，而猫免疫缺陷病毒可能更重要。需要进一步研究来调查澳大利亚患有淋巴肉瘤的猫的品种易感性以及猫白血病病毒和猫免疫缺陷病毒状况。
