Laude D, Girard A, Consoli S, Mounier-Vehier C, Elghozi J L
Centre de Pharmacologie Clinique, CNRS URA 1482, Faculté de Médecine Necker, Paris, France.
Clin Exp Hypertens. 1997 Jul-Aug;19(5-6):901-11. doi: 10.3109/10641969709083194.
The cardiovascular reactivation to a recently described videogame task i.e. a maze test was evaluated in the time and frequency-domain using finger blood pressure (BP) measurement in 25 subjects on no medication, including 6 subjects with mild hypertension. Prior to BP measures subjects completed the items of the State-Trait Anger Expression Inventory questionnaire corresponding to the trait anger and anger expression scales. The BP recording session was divided into resting, test and recovery periods. A detrending procedure was applied to each recording prior to the fast Fourier transform. Systolic BP (SBP) and heart rate (HR) were increased during the test. The mid-frequency (MF, 0.1 Hz) components of SBP and HR variability were also elevated during the stressful period. In resting conditions SBP levels of subjects with low trait anger was lower than in subjects with high trait anger (128 +/- 4 mmHg, n = 14 versus 148 +/- 4 mmHg, n = 11, P < 0.01, Student t test). Nevertheless the average SBP increase due to the stress was of similar magnitude in these two subgroups (14 mmHg). A significant negative relationship was observed between anger-out expression score and the MF SBP variation (r = 0.46, P < 0.05). A significant negative relation was found between anger-in mode of expression and the HR peak during the test (r = 0.43, P < 0.05). In conclusion, our data suggest that individuals who are often in anger-provoking situations (high trait anger) should have heightened BP. Two different patterns of cardiovascular responses (SBP variability and HR levels) were observed for the outward and inward mode of expression of anger. This may reflect a different psychological control of HR levels and BP variability.
在25名未服用药物的受试者（包括6名轻度高血压患者）中，使用手指血压测量法，在时域和频域评估了对最近描述的一项电子游戏任务（即迷宫测试）的心血管反应。在进行血压测量之前，受试者完成了与特质愤怒和愤怒表达量表相对应的状态-特质愤怒表达量表问卷项目。血压记录时段分为静息期、测试期和恢复期。在进行快速傅里叶变换之前，对每个记录应用去趋势程序。测试期间收缩压（SBP）和心率（HR）升高。在压力期，SBP和HR变异性的中频（MF，0.1Hz）成分也升高。在静息状态下，特质愤怒低的受试者的SBP水平低于特质愤怒高的受试者（128±4mmHg，n = 14，对比148±4mmHg，n = 11，P < 0.01，学生t检验）。然而，这两个亚组中由于压力导致的平均SBP升高幅度相似（14mmHg）。愤怒表达得分与MF SBP变化之间存在显著负相关（r = 0.46，P < 0.05）。在测试期间，愤怒内化表达模式与HR峰值之间存在显著负相关（r = 0.43，P < 0.05）。总之，我们的数据表明，经常处于易激惹情境（特质愤怒高）的个体血压应会升高。观察到愤怒的外向和内向表达模式有两种不同的心血管反应模式（SBP变异性和HR水平）。这可能反映了对HR水平和BP变异性的不同心理控制。
