Hanker J S, Silverman M S, Romanovicz D K
Histochem J. 1977 Nov;9(6):729-44. doi: 10.1007/BF01003067.
A new distinctive and unique peroxisomal organelle with a spindle shape has been observed in luminal epithelial cells of striated and excretory ducts of mouse salivary glands. Light microscopic studies indicate it has an ellipsoidal centre from which catalase-positive filamentous or rod-like processes protrude along its major axis; hence, it is called a phi body. A role for this specialized peroxisome in the formation of nearby free filaments and rods is suggested by the frequent observation of segmentation of its axial processes. Complementary ultrastructural studies of osmium-fixed preparations show that the deformation to an oval shape results from the pressure of the extruding crystalloid coincident with the major axis of the ellipsoidal body. The size range and conformation of phi body axial processes are comparable to those of free catalase-positive rods and filaments observed in the same cells. The periodic substructure of the crystalloid in the phi body core is identical with that of nearby cytoplasmic rods. These observations are consistent with the view that the rods and filaments observed free in the cytoplasm are formed by extrusion from the crystalloid core of the phi body. phi Bodies could also be responsible for the Aver rods of leukemic leukocytes.
在小鼠唾液腺横纹管和排泄管的腔上皮细胞中观察到一种新的、独特的纺锤形过氧化物酶体细胞器。光学显微镜研究表明，它有一个椭圆形中心，过氧化氢酶阳性的丝状或棒状突起沿其长轴从该中心伸出；因此，它被称为φ小体。其轴向突起的频繁分割现象表明，这种特殊的过氧化物酶体在附近游离丝状物和棒状物的形成中发挥作用。对锇固定制剂的补充超微结构研究表明，其变形为椭圆形是由与椭球体长轴一致的挤出晶体的压力所致。φ小体轴向突起的大小范围和形态与在同一细胞中观察到的游离过氧化氢酶阳性棒状物和丝状物相当。φ小体核心中晶体的周期性亚结构与附近细胞质棒状物的亚结构相同。这些观察结果与以下观点一致，即细胞质中观察到的游离棒状物和丝状物是由φ小体的晶体核心挤出形成的。φ小体也可能与白血病白细胞的Aver棒状物有关。
