Mori K, Tominaga K, Hirose T, Sasagawa M, Yokoyama K, Moriyama N
Department of Thoracic Diseases, Tochigi Cancer Center, Utsunomiya City, Japan.
J Thorac Imaging. 1997 Jul;12(3):173-80. doi: 10.1097/00005382-199707000-00002.
We evaluated the usefulness of low-dose helical computed tomography (CT) as a routine second step in patients screened for lung cancer with plain chest radiography (PCR). Of 5,437 people who underwent mass screening for lung cancer by PCR, further work-up was required for 230 because of abnormal findings. Of 221 subjects who had CT as a second step, abnormal shadows were detected in 110 and no abnormal shadows were seen in 111. Screening CT (helical scan; beam collination, 10 mm; pitch of 2:20 mm/s; and tube current, 50 mA) detected 17 lung cancers, 87 benign lesions, and 6 extrapulmonary lesions, with an average diameter of 10 mm (range, 2-35 mm). All lung cancers were peripheral (12 stage I, 4 stage IIIA, and 1 stage IV). In 40% of screened subjects, 37 with benign lesions and 7 with lung cancer (6 stage I), lesions were delineated only by screening CT. In conclusion, low-dose helical CT was found to be useful as a second step in patients who have been screened for lung cancer by PCR and can delineate the early stage of lung cancer.
我们评估了低剂量螺旋计算机断层扫描（CT）作为对接受胸部X线平片（PCR）肺癌筛查患者的常规第二步检查的实用性。在5437例接受PCR肺癌大规模筛查的人群中，由于发现异常，230人需要进一步检查。在221例接受CT作为第二步检查的受试者中，110例检测到异常阴影，111例未见异常阴影。筛查CT（螺旋扫描；线束准直，10mm；螺距2:20mm/s；管电流，50mA）检测到17例肺癌、87例良性病变和6例肺外病变，平均直径为10mm（范围2 - 35mm）。所有肺癌均为周围型（12例I期，4例IIIA期，1例IV期）。在40%的筛查受试者中，37例为良性病变患者，7例为肺癌患者（6例I期），病变仅通过筛查CT得以明确。总之，发现低剂量螺旋CT作为对接受PCR肺癌筛查患者的第二步检查是有用的，并且能够明确肺癌的早期阶段。
