Umeda H, Yoshimura Y, Yamaguchi O, Kumakawa K, Shiraiwa Y
Department of Urology, Fukushima Medical College.
Hinyokika Kiyo. 1997 Jun;43(6):415-9.
Between April 1994 and March 1995, transurethral balloon laser thermotherapy (TUBAL-T) using Prostalase was performed on 53 patients with benign prostatic hyperplasia. Clinical efficacy was evaluated at 3 months after TUBAL-T. The mean international prostate symptom score (I-PSS) decreased from 21.5 at baseline to 11.3 after 3 months (p < 0.0001). Irritative (the sum of items 1, 2, 4 and 7 of I-PSS) decreased by 55%, while obstructive symptoms (the sum of items 3, 5 and 6 of I-PSS) by 45%. However, other objective parameters such as maximum flow rate, voided volume, percent postvoid residual volume and prostate volume showed no significant change (7.8 to 7.2 ml/s, 130 to 147 ml, 33 to 28% and 39.7 to 41.0 ml, respectively). In conclusion, significant improvement after TUBAL-T was observed for subjective symptoms, especially irritative symptoms, but not for objective parameters.
1994年4月至1995年3月期间，对53例良性前列腺增生患者采用前列腺酶进行经尿道球囊激光热疗（TUBAL-T）。在TUBAL-T治疗3个月后评估临床疗效。国际前列腺症状评分（I-PSS）平均值从基线时的21.5降至3个月后的11.3（p < 0.0001）。刺激性症状（I-PSS第1、2、4和7项之和）下降了55%，而梗阻性症状（I-PSS第3、5和6项之和）下降了45%。然而，其他客观参数，如最大尿流率、排尿量、排尿后残余尿量百分比和前列腺体积均无显著变化（分别从7.8降至7.2 ml/s、从130增至147 ml、从33%降至28%、从39.7增至41.0 ml）。总之，TUBAL-T治疗后主观症状，尤其是刺激性症状有显著改善，但客观参数无改善。
