血小板蛋白的脂肪酸酰化作用。
Fatty acid acylation of platelet proteins.
作者信息
Van Cott E M, Muszbek L, Laposata M
机构信息
Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114-2696, USA.
出版信息
Prostaglandins Leukot Essent Fatty Acids. 1997 Jul;57(1):33-7. doi: 10.1016/s0952-3278(97)90490-7.
A variety of fatty acids can become covalently attached to platelet proteins by thioester linkage. These fatty acids include palmitate, myristate, stearate, arachidonate, and eicosapentaenoate. More than 20 platelet proteins can be acylated by fatty acids. Several of the acylated platelet proteins have been identified, including glycoprotein Ib beta, glycoprotein IX, P-selectin, G-protein alpha subunits, and CD9. This report reviews the fatty acid acylation of platelet proteins.
多种脂肪酸可通过硫酯键与血小板蛋白共价结合。这些脂肪酸包括棕榈酸、肉豆蔻酸、硬脂酸、花生四烯酸和二十碳五烯酸。20多种血小板蛋白可被脂肪酸酰化。已鉴定出几种被酰化的血小板蛋白，包括糖蛋白Ibβ、糖蛋白IX、P-选择素、G蛋白α亚基和CD9。本报告综述了血小板蛋白的脂肪酸酰化。
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