Chugh S N, Pal R, Singh V, Seth S
Dept. of Medicine and Biochemistry, Pt. B.D. Sharma Medical College, Rohtak.
J Assoc Physicians India. 1996 Mar;44(3):184-5.
Serial blood phosphine (PH3) levels were done in patients with severe (Group I, n = 30), mild (Group 2, n = 10) and minimal or nil toxicity due to aluminium phosphide compound. Blood phosphine levels were significantly higher (p < 0.001) in patients of Group I than other two groups. Phosphine was not detectable in Group 3 patients. Therefore, blood phosphine levels were positively correlated to clinical grades of toxicity and to dose of active pesticide consumed. Higher the blood phosphine, higher was the mortality. Patients having blood phosphine levels equal to or less than 1.067 +/- 0.16 mg% survived, hence, it appeared to be limit of phosphine toxicity.
对因磷化铝化合物导致严重中毒(第一组,n = 30)、轻度中毒(第二组,n = 10)以及最小或无毒性的患者进行了系列血中磷化氢(PH3)水平检测。第一组患者的血中磷化氢水平显著高于其他两组(p < 0.001)。第三组患者中未检测到磷化氢。因此,血中磷化氢水平与中毒临床分级以及摄入的活性农药剂量呈正相关。血中磷化氢水平越高,死亡率越高。血中磷化氢水平等于或低于1.067 +/- 0.16 mg%的患者存活,因此,这似乎是磷化氢毒性的限度。