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人垂体催乳素(hPRL):完整的线性氨基酸序列。

Human pituitary prolactin (hPRL): the entire linear amino acid sequence.

作者信息

Shome B, Parlow A F

出版信息

J Clin Endocrinol Metab. 1977 Nov;45(5):1112-5. doi: 10.1210/jcem-45-5-1112.

DOI:10.1210/jcem-45-5-1112
PMID:925136
Abstract

For the first time the entire linear amino acid sequence of hPRL has been ascertained. The sequence features 198 amino acid residues, leucine at the NH2-terminus, and 6 half custines. hPRL sequence identity with porcine, ovine, and rat PRL is 77, 73, and 60%, respectively. However, hPRL sequence identity with hGH is only 16%, and with human placental lactogen 13%.

摘要

首次确定了人催乳素(hPRL)完整的线性氨基酸序列。该序列由198个氨基酸残基组成,氨基端为亮氨酸,还有6个半胱氨酸。hPRL与猪、羊和大鼠催乳素的序列同源性分别为77%、73%和60%。然而,hPRL与人生长激素(hGH)的序列同源性仅为16%,与人类胎盘催乳素的序列同源性为13%。

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Human pituitary prolactin (hPRL): the entire linear amino acid sequence.人垂体催乳素(hPRL):完整的线性氨基酸序列。
J Clin Endocrinol Metab. 1977 Nov;45(5):1112-5. doi: 10.1210/jcem-45-5-1112.
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引用本文的文献

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Species-specificity of growth-promoting effects of prolactin during rat embryogenesis.催乳素在大鼠胚胎发育过程中促生长作用的物种特异性。
J Anat. 1998 Jan;192 ( Pt 1)(Pt 1):1-12. doi: 10.1046/j.1469-7580.1998.19210001.x.
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Glycosylated equine prolactin and its carbohydrate moiety.糖基化马催乳素及其碳水化合物部分。
J Protein Chem. 1996 Jul;15(5):413-26. doi: 10.1007/BF01886848.
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Chromosomal localization of the human placental lactogen-growth hormone gene cluster to 17q22-24.人胎盘催乳素-生长激素基因簇在染色体上定位于17q22 - 24。
Am J Hum Genet. 1982 Mar;34(2):227-34.
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Virchows Arch A Pathol Anat Histopathol. 1982;398(1):19-31. doi: 10.1007/BF00585610.
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Nucleic Acids Res. 1983 Jun 25;11(12):3939-58. doi: 10.1093/nar/11.12.3939.
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