Koitabashi T, Satoh N, Takino Y
Department of Anesthesiology, Ichikawa General Hospital, Tokyo Dental College.
Masui. 1997 Jul;46(7):975-7.
We report a case of delayed recovery after the termination of propofol and nitrous oxide anesthesia. On the preoperative examination hepatic dysfunction (Indocyanine green (ICG) plasma retention rate at 15 minutes of 22%) was pointed out. Anesthesia was maintained with epidural block, nitrous oxide, oxygen and propofol. Average infusion rate of propofol was 5-6 mg.kg-1.h-1. Although at the end of the operation, the propofol infusion and nitrous oxide were stopped simultaneously, 59 minutes were necessary before the emergence from anesthesia. We consider that an average infusion rate of propofol should be decelerated in a case of ICG clearance time elongation.
我们报告一例丙泊酚和氧化亚氮麻醉终止后恢复延迟的病例。术前检查发现肝功能障碍（15分钟吲哚菁绿（ICG）血浆潴留率为22%）。采用硬膜外阻滞、氧化亚氮、氧气和丙泊酚维持麻醉。丙泊酚的平均输注速率为5-6mg·kg-1·h-1。尽管手术结束时丙泊酚输注和氧化亚氮同时停止，但仍需要59分钟才能从麻醉中苏醒。我们认为，在ICG清除时间延长的情况下，应降低丙泊酚的平均输注速率。
