Canavero Sergio, Bonicalzi Vincenzo
Pain Relief Unit, Department of Neurosciences, University of Turin, Ospedale Molinette,Turin,Italy.
Pain. 1996 Nov;68(1):179-181. doi: 10.1016/S0304-3959(96)03168-5.
Central pain remains a therapeutic challenge. We report beneficial effects of lamotrigine, a novel antiepileptic drug, on four patients suffering from long-standing central pain. Analgesia may be due to interference with glutamatergic transmission.