Guerrini R, Belmonte A, Veggiotti P, Mattia D, Bonanni P
Institute of Child Neurology and Psychiatry, University of Pisa, IRCCS Stella Maris Foundation, Italy.
Brain Dev. 1997 Jul;19(5):343-6. doi: 10.1016/s0387-7604(97)00033-8.
Childhood epilepsy with occipital paroxysms is an age-related idiopathic focal epilepsy. Occipital EEG paroxysms are considered necessary for diagnosis. We carried out a close clinical and EEG follow-up (range, 2-12 years; mean, 6 years 7 months; median, 7 years) in 24 patients (age range, 4-19 years; mean, 11 years 8 months; median, 11 years). In five children with early seizure onset and particularly benign prognosis without any treatment, EEG abnormalities appeared 3-10 months after the first seizure. Four of them exhibited the ictal pattern of versive seizures with vomiting. Our findings confirm that in the early idiopathic focal seizure disorders, interictal EEG abnormalities may be lacking at the beginning of the disorder.
儿童枕叶阵发性癫痫是一种与年龄相关的特发性局灶性癫痫。枕叶脑电图阵发性活动被认为是诊断的必要条件。我们对24例患者(年龄范围4 - 19岁;平均11岁8个月;中位数11岁)进行了密切的临床和脑电图随访(范围2 - 12年;平均6年7个月;中位数7年)。5例起病早且预后特别良好未接受任何治疗的儿童,脑电图异常在首次发作后3 - 10个月出现。其中4例表现为伴有呕吐的旋转性发作的发作期模式。我们的研究结果证实,在早期特发性局灶性癫痫发作疾病中,发作间期脑电图异常在疾病开始时可能不存在。