Michailova K N
Department of Anatomy and Histology, Preclinical University Center, Faculty of Medicine, Medical University, Sofia, Bulgaria.
Eur J Morphol. 1997 Apr;35(2):125-35. doi: 10.1076/ejom.35.2.125.13063.
Visceral pleura with underlying lung parenchyma was obtained following thoracotomy carried out in 21 patients of both sexes, aged 27-56 years. The samples were taken from unaltered lung regions, and were studied using transmission electron microscopy (TEM). The main components of the visceral pleural tissue complex, mesothelium, basal lamina (BL), elastic membrane (EM), and submesothelial connective tissue layer, are described, with special reference to their relations with the corresponding structures of the lung interstitium. These elements have significant quantitative regional diversities but can be recognized in all investigated cases, and show constant structural uniformity. Two basic mesothelial cell types, squamous (flat) and cuboidal (high) are discerned, based on the differences in size, shape, cell organelles and membrane specialization. The cuboidal mesothelial cells are especially characteristic for the visceral pleura. In addition, an intermediate mesothelial cell that apparently represents a stage in the development of a squamous to a cubiodal mesothelial cell is fairly common. For more rarely, degenerative mesothelial cells are found.
在21例年龄在27至56岁的男女患者中，开胸术后获取了带有肺实质的脏胸膜。样本取自未改变的肺区域，并使用透射电子显微镜（TEM）进行研究。描述了脏胸膜组织复合体的主要成分，即间皮、基膜（BL）、弹性膜（EM）和间皮下结缔组织层，并特别提及它们与肺间质相应结构的关系。这些成分在区域上有显著的数量差异，但在所有研究病例中均可识别，且结构具有恒定的一致性。基于大小、形状、细胞器和膜特化的差异，可辨别出两种基本的间皮细胞类型，即鳞状（扁平）和立方状（高柱状）。立方状间皮细胞是脏胸膜的特别特征。此外，一种中间型间皮细胞相当常见，它显然代表了从鳞状间皮细胞向立方状间皮细胞发育的一个阶段。更罕见的是，还发现了退化的间皮细胞。
