Marie B, Labouyrie E, Scheid P, Siat J, Ménard O, Cosmidis I, Plénat F, Vignaud J M
Laboratoire d'Anatomie Pathologique, Hôpital Haut-Lévèque Bordeaux, France.
Histopathology. 1997 Jul;31(1):83-6. doi: 10.1046/j.1365-2559.1997.5820823.x.
We present the clinical and histopathological findings of an unusual pulmonary cystic lymphoepithelial lesion in an HIV sero-positive patient.
The 32-year-old female patient developed two nodules in the vicinity of the right and left hila. Left upper lobectomy showed a 40-mm wide cystic lesion. The cyst wall was lined by a squamous epithelium and lymphoid tissue with a marked follicular hyperplasia and a prominent follicular cell dendritic network expressing HIV major core protein p24.
The absence of an Epstein-Barr virus infected lymphoid population and monoclonal immunoglobulin gene rearrangement supported the benign nature of the lesion.
我们展示了一名HIV血清阳性患者罕见的肺囊性淋巴上皮病变的临床和组织病理学发现。
这位32岁的女性患者在左右肺门附近出现了两个结节。左上叶切除显示一个40毫米宽的囊性病变。囊肿壁内衬鳞状上皮和淋巴组织，伴有明显的滤泡增生和表达HIV主要核心蛋白p24的显著滤泡细胞树突状网络。
无爱泼斯坦-巴尔病毒感染的淋巴细胞群和单克隆免疫球蛋白基因重排支持该病变的良性性质。
