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60例艾滋病患者的临床和实验室特征:一项南印度研究。

Clinical and laboratory profile of sixty patients with AIDS: a South Indian study.

作者信息

George J, Hamide A, Das A K, Amarnath S K, Rao R S

机构信息

Department of Medicine, Jawaharlal Institute of Post Graduate Medical Education and Research (JIPMER), Pondicherry, South India.

出版信息

Southeast Asian J Trop Med Public Health. 1996 Dec;27(4):686-91.

PMID:9253867
Abstract

Sixty patients who fulfilled the WHO case definition of acquired immunodeficiency syndrome (AIDS) were admitted and treated between January 1993 and June 1995 in JIPMER Hospital, Pondicherry, South India. Their mean age was 30.3 +/- 6.4 years. Male: female ratio was 5 : 1. The heterosexual route was the major mode of transmission (96.7%). Fever was the commonest presentation (98.3%), followed by weight loss (85%) and cough (36.7%). The commonest opportunistic infection seen was tuberculosis (pulmonary, extrapulmonary - single or in combination) followed by esophageal candidiasis. Cryptococcal meningitis, intestinal crytosporidiosis, CNS toxoplasmosis, Pneumocystis pneumonia and group B Salmonella septicemia were the other infections encountered. Ten out of the 38 patients with tuberculosis were followed up on antituberculous treatment for 6 months. Seven out of 18 patients with esophageal candidiasis were treated with ketoconazole.

摘要

1993年1月至1995年6月期间,印度南部本地治里的贾瓦哈拉尔·尼赫鲁医学院医院收治并治疗了60例符合世界卫生组织获得性免疫缺陷综合征(艾滋病)病例定义的患者。他们的平均年龄为30.3±6.4岁。男女比例为5∶1。异性传播途径是主要传播方式(96.7%)。发热是最常见的症状(98.3%),其次是体重减轻(85%)和咳嗽(36.7%)。最常见的机会性感染是结核病(肺结核、肺外结核——单发或合并),其次是食管念珠菌病。还遇到了隐球菌性脑膜炎、肠道隐孢子虫病、中枢神经系统弓形虫病、肺孢子菌肺炎和B组沙门菌败血症等其他感染。38例结核病患者中有10例接受了6个月的抗结核治疗随访。18例食管念珠菌病患者中有7例接受了酮康唑治疗。

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