Serra-Serra V, Kyle P M, Chandran R, Redman C W
University of Oxford, Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Maternity Hospital.
Br J Obstet Gynaecol. 1997 Aug;104(8):904-9. doi: 10.1111/j.1471-0528.1997.tb14349.x.
To study changes throughout gestation and the puerperium of middle cerebral artery flow velocity waveforms obtained by transcranial Doppler ultrasound.
Prospective, observational study.
John Radcliffe Maternity Hospital, Oxford, UK.
Middle cerebral artery velocities were measured by transcranial Doppler ultrasound in 25 nonpregnant women, 22 women longitudinally followed throughout pregnancy and 21 women serially studied from delivery until the late puerperium.
Transcranial Doppler changes in pregnancy and the puerperium.
The transcranial Doppler ultrasound measurements showed good reproducibility. Signals from one middle cerebral artery could not be obtained in 4.6% of the examinations, but otherwise readings were similar on both sides. Women in the second half of pregnancy had lower middle cerebral artery mean velocities than nonpregnant women. Velocities decreased with advancing gestation but increased in the immediate puerperium to levels comparable to those found in nonpregnant women.
Transcranial Doppler ultrasound is a noninvasive technique suitable for studying maternal cerebral haemodynamics in pregnancy and postpartum. Middle cerebral artery mean velocity decreased with advancing gestation and increased to nonpregnant values in the immediate puerperium. These physiological changes need to be considered when comparing data with measurements taken in abnormal pregnancy states.
研究经颅多普勒超声获取的大脑中动脉血流速度波形在整个妊娠期及产褥期的变化。
前瞻性观察性研究。
英国牛津约翰·拉德克利夫妇产医院。
对25名未孕女性、22名在整个孕期进行纵向随访的女性以及21名从分娩至产褥晚期进行系列研究的女性，采用经颅多普勒超声测量大脑中动脉速度。
妊娠期及产褥期经颅多普勒的变化。
经颅多普勒超声测量显示出良好的可重复性。在4.6%的检查中无法获取一侧大脑中动脉的信号，但除此之外，两侧读数相似。妊娠后半期女性的大脑中动脉平均速度低于未孕女性。速度随孕周增加而降低，但在产褥早期升高至与未孕女性相当的水平。
经颅多普勒超声是一种适用于研究孕期及产后母体脑血流动力学的非侵入性技术。大脑中动脉平均速度随孕周增加而降低，并在产褥早期升至未孕时的值。在将数据与异常妊娠状态下的测量值进行比较时，需要考虑这些生理变化。
