Vandecandelaere M, Cortet B, Flipo R M, Duquesnoy B, Delcambre B
Clinique rhumatologique, centre André-Verhaeghe, CHU, hôpital Roger-Salengro, Lille, France.
Rev Med Interne. 1997 Jul;18(7):571-4. doi: 10.1016/s0248-8663(97)80810-7.
Two women, 31 and 19 years old, developed acute back pain with non-traumatic vertebral fractures one month after delivery in one case, and during the 9th month of gestation in the second case. For the first patient, the evolution was favorable with an increase of bone mineral density (15.2% over fourteen months under calcium and vitamin D). Ten years later, the osteoporosis of the second patient worsened without any new pregnancy. Our observations suggest the possibility of different pathogenies in pregnancy-associated osteoporosis.
两名女性，分别为31岁和19岁，一例在产后一个月出现急性背痛并伴有非创伤性椎体骨折，另一例在妊娠第9个月出现。对于首例患者，病情进展良好，骨矿物质密度有所增加（在补充钙和维生素D的情况下，14个月内增加了15.2%）。十年后，第二例患者的骨质疏松症在没有再次怀孕的情况下病情恶化。我们的观察结果提示妊娠相关性骨质疏松症可能存在不同的发病机制。
