Hjaltason H, Tegnér R
Division of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Neuropsychologia. 1997 Aug;35(8):1175-9. doi: 10.1016/s0028-3932(97)00047-x.
Left hand use in left hemispace has been shown to reduce left neglect. Right hand use can theoretically increase neglect by right spatial cueing and left hemisphere activation. The aim of the present study was to investigate the role of right hand use and right hemisphere activation in left neglect by dissociating hemisphere activation from the hemispace in which the motor response is made. Twelve neglect patients performed line bisection by two means: with their right hand and with a lamp mounted centrally on the forehead ('miner's lamp'). Lamp use induces left and right hemisphere activation without hemispace involvement. Bisection with the lamp and the hand were done with right, left and neutral cues. No difference was found in bisection performance between lamp and right hand use, and no interaction between lamp/hand use and cueing. This indicates that right hand use per se does not influence neglect in line bisection. It is suggested that the apparent lack of right hemisphere activation with lamp use is due to the widespread right-sided lesion of the typical neglect patient.
已证实，在左半空间使用左手可减少左侧空间忽视。理论上，使用右手会因右侧空间提示和左半球激活而增加忽视。本研究的目的是通过将半球激活与产生运动反应的半空间分离，来探究右手使用和右半球激活在左侧空间忽视中的作用。12名忽视患者通过两种方式进行直线二等分：用右手和使用安装在前额中央的灯（“矿灯”）。使用灯可在不涉及半空间的情况下诱导左、右半球激活。使用灯和手进行二等分时设置了右侧、左侧和中性提示。结果发现，使用灯和右手进行二等分的表现没有差异，且灯/手的使用与提示之间没有相互作用。这表明，仅右手使用本身不会影响直线二等分中的忽视。有人提出，使用灯时右半球激活明显缺乏是由于典型忽视患者普遍存在右侧病变。
