Paduch D A, Niedzielski J
Department of Pediatric Surgery, University School of Medicine, Lodz, Poland.
J Urol. 1997 Sep;158(3 Pt 2):1128-32. doi: 10.1097/00005392-199709000-00111.
We designed a randomized prospective study of male adolescents with moderate and severe varicoceles to determine whether prophylactic varicocele repair is beneficial.
We evaluated 2,100 boys (10 to 20 years old) for genitourinary abnormalities. From this population 2 groups of adolescents 15 to 19 years old with grade 2 or 3 varicoceles were created, including 88 who underwent varicocele repair and 36 controls. Testicular volume and pampiniform vein diameter were measured, and Doppler ultrasound was performed.
After 12 months volume of the involved left testis increased to almost normal in treated boys (mean atrophy index 12.7% at surgery and 3% 12 months later). In controls the corresponding atrophy indexes were 10 and 9%, respectively. The relative increase in left testicular volume was 26% in the surgery group and 11% in controls. In the surgery group mean pampiniform vein diameter decreased from 2.8 preoperatively to 2 mm. postoperatively but there was no change in controls.
Varicocele repair in adolescents with moderate and severe varicocele reversed testicular growth arrest and resulted in catch-up growth within 12 month of surgery.
我们设计了一项针对患有中度和重度精索静脉曲张的男性青少年的随机前瞻性研究，以确定预防性精索静脉曲张修复术是否有益。
我们对2100名男孩（10至20岁）进行了泌尿生殖系统异常评估。从该人群中选取了两组15至19岁患有2级或3级精索静脉曲张的青少年，其中88人接受了精索静脉曲张修复术，36人为对照组。测量了睾丸体积和蔓状静脉丛直径，并进行了多普勒超声检查。
12个月后，接受治疗的男孩中受累左侧睾丸的体积几乎恢复正常（手术时平均萎缩指数为12.7%，12个月后为3%）。对照组的相应萎缩指数分别为10%和9%。手术组左侧睾丸体积的相对增加为26%，对照组为11%。手术组蔓状静脉丛的平均直径从术前的2.8毫米降至术后的2毫米，而对照组无变化。
对患有中度和重度精索静脉曲张的青少年进行精索静脉曲张修复术可逆转睾丸生长停滞，并在手术12个月内实现追赶生长。
