Noorily S H, Hantler C B, Sako E Y
Department of Anesthesiology, University of Texas Health Science Center, San Antonio 78284-7838, USA.
South Med J. 1997 Aug;90(8):836-8. doi: 10.1097/00007611-199708000-00014.
There are well-recognized adverse interactions between the monoamine oxidase inhibitors and anesthetic drugs, particularly narcotics. Patients having cardiopulmonary bypass procedures are commonly anesthetized using high-dose narcotic techniques. We describe an uneventful perioperative course in a parkinsonian patient who required urgent coronary artery bypass graft surgery while he was taking selegiline, a selective inhibitor of monoamine oxidase type B.
单胺氧化酶抑制剂与麻醉药物之间存在已得到充分认识的不良相互作用,尤其是与麻醉性镇痛药。接受体外循环手术的患者通常采用大剂量麻醉性镇痛药技术进行麻醉。我们描述了一名帕金森病患者在服用单胺氧化酶B型选择性抑制剂司来吉兰期间需要紧急进行冠状动脉搭桥手术时,围手术期过程顺利的情况。