Fiedorowicz Jess G, Swartz Karen L
The Johns Hopkins Hospital, Dept. of Psychiatry, Baltimore, MD 21287-7131, USA.
J Psychiatr Pract. 2004 Jul;10(4):239-48. doi: 10.1097/00131746-200407000-00005.
The use of monoamine oxidase inhibitors (MAOIs) by psychiatrists has declined over the past several decades with the expansion of psychiatrists' pharmacologic armamentarium. This trend has also been driven by concern about food and drug interactions and side effects, as well as waning physician experience with these medications. Many psychiatrists, in fact, never prescribe MAOIs. Recent research has liberalized the MAOI diet and identified symptom presentations more likely to respond to these medications. Thus, clinicians must continue to familiarize themselves with the properties of and indications for prescribing MAOIs.
在过去几十年中,随着精神科医生可用药物种类的增加,精神科医生对单胺氧化酶抑制剂(MAOIs)的使用有所减少。这一趋势还受到对食物与药物相互作用及副作用的担忧,以及医生对这些药物的经验逐渐减少的影响。事实上,许多精神科医生从未开过MAOIs的处方。最近的研究放宽了MAOI饮食限制,并确定了更可能对这些药物有反应的症状表现。因此,临床医生必须继续熟悉MAOIs的特性和处方适应证。