Halme S, Surcel H M
National Public Health Institute, Oulu, Finland.
Scand J Infect Dis Suppl. 1997;104:18-21.
The association of Chlamydia pneumoniae to several chronic diseases such as atherosclerosis has been suggested serologically and by direct demonstration of organisms in disease lesions. Cell mediated immunity is crucial in host defense against intracellular pathogens such as C. pneumoniae. C. pneumoniae is a relatively recently recognized pathogen and the cellular mechanisms in C. pneumoniae immunity have so far remained unstudied. The present review includes the data available on C. pneumoniae proteins and their role as T cell activating antigens and Th1/Th2 balance in C. pneumoniae immunity.
肺炎衣原体与动脉粥样硬化等多种慢性疾病之间的关联已通过血清学以及在疾病病灶中直接检测到病原体得到证实。细胞介导的免疫在宿主抵御肺炎衣原体等细胞内病原体的过程中至关重要。肺炎衣原体是一种相对较新被认识的病原体，迄今为止，肺炎衣原体免疫中的细胞机制尚未得到研究。本综述涵盖了关于肺炎衣原体蛋白质及其作为T细胞激活抗原的作用以及肺炎衣原体免疫中Th1/Th2平衡的现有数据。
