Kates R E, Jones C L
J Pharm Sci. 1977 Oct;66(10):1490-2. doi: 10.1002/jps.2600661040.
A rapid GLC method for measuring plasma propranolol levels is reported. 4-Methylpropranolol was utilized as an internal standard. Pentafluoropropionate derivatives of propranolol and the internal standard eluted rapidly and gave good sensitivity under the conditions employed. The advantage of this procedure over previously reported methods is the speed of analysis, which is facilitated by rapid elution of contaminant peaks.
报道了一种用于测量血浆普萘洛尔水平的快速气相色谱法。4-甲基普萘洛尔用作内标。普萘洛尔及其内标的五氟丙酸酯衍生物洗脱迅速，在所采用的条件下具有良好的灵敏度。该方法相对于先前报道的方法的优点是分析速度快，这得益于污染物峰的快速洗脱。
